Catalog Number - 68508-05P-4

Cogent RP C8™ HPLC Columns are designed for reliable reversed-phase chromatography using a traditional octyl (C8) bonded stationary phase. Manufactured with ultra-high purity silica and fully double end capped bonding technology, these columns provide consistent retention, excellent peak shape, and long service life. The RP C8™ phase is a USP L7 equivalent chemistry and is commonly used as an alternative for methods developed on similar C8 columns. Compared to C18 phases, RP C8™ columns generally provide less hydrophobic retention while maintaining excellent selectivity for many neutral and non-polar compounds.

68508-05P-4 is packed with 5 µm RP C8™ particles featuring a 100 Å pore size in a 4.0 mm ID x 50 mm length format. The short column length is well suited for rapid analyses, method scouting, and high-throughput workflows where fast run times are desired. The 5 µm particle size provides low backpressure and dependable chromatographic performance on conventional HPLC systems. This column is particularly useful for hydrophobic compounds, neutral analytes, and long-chain fatty acids where slightly reduced retention compared to a C18 stationary phase is advantageous.

The 4.0 mm internal diameter offers a balance between sensitivity, solvent consumption, and compatibility with traditional analytical HPLC systems. The short 50 mm format allows analysts to quickly evaluate chromatographic selectivity and optimize separation conditions before transitioning methods to longer analytical or preparative column formats.

Key Benefits

• RP C8™ stationary phase

• USP L7 equivalent chemistry

• Octyl (C8) bonded phase

• Fully double end capped

• Ultra-high purity silica support

• 100 Å pore size

• Fast 50 mm column length

• Lower retention than C18 phases

• Low backpressure with 5 µm particles

• Suitable for method development and scouting

Typical Applications

• Reversed-phase HPLC

• Method development

• Method scouting

• Long-chain fatty acid analysis

• Hydrophobic compound separations

• Neutral compound analysis

• Pharmaceutical analysis

• Environmental analysis

• Food and beverage testing

• Routine analytical testing

Specifications

• Product Type: HPLC Column

• Stationary Phase: RP C8™

• USP Classification: L7

• Chromatography Mode: Reversed Phase

• Bonded Phase: Octyl (C8)

• Endcapping: Fully Double End Capped

• Particle Size: 5 µm

• Pore Size: 100 Å

• Column Dimensions: 4.0 mm ID x 50 mm

• Recommended Flow Rate: 0.8-1.5 mL/min

• Column Hardware: Stainless Steel

• Brand: Cogent

Special Order Item Information

• Please review the Special Order Item Information for complete details.

• For pricing confirmation, availability, lead times, or application assistance, please contact MICROSOLV Customer Service.

Important Notes

• Designed for fast reversed-phase HPLC analyses

• Provides lower retention than comparable C18 columns

• Suitable for hydrophobic and moderately non-polar compounds

• Excellent choice for long-chain fatty acid separations

• Frequently used for method development and method scouting

• 50 mm length helps reduce analysis times and solvent consumption

• 5 µm particles provide low backpressure and broad instrument compatibility

• Compatible with standard HPLC systems operating at conventional flow rates

• Manufactured using ultra-high purity silica and fully double end capped bonding technology

• This is a Special Order Item